Futhermore, IM has also been reported to fail to control disease progression in the absence of BCR/ABL mutations, an aspect that remains poorly understood [9], [10].
G-CSF has been reported to fail to mobilize a sufficient number of PBSCs for transplantation in some elderly patients and especially in patients with a history of chemotherapy or radiotherapy [ 69, 84, 85, 93, 97, 103].
However, hip arthroplasty surgery in younger patients with more demanding lifestyles has been reported to fail earlier (Tennent and Goddard 2000, Lewthwaite et al. 2008, Howcroft et al. 2008).
Game bird reintroductions have been reported to fail because of behavioural deficiencies, post-release predation, lower disease resistance, disease outbreaks, and genetic differences between the released and the wild birds [ 3, 5- 7].
As half of sgRNAs have been reported to fail in C. elegans (Kim et al. 2014), I mutated two PAMs in the oligo to allow knock-in attempts with different sgRNAs.
However, microscopic assessments might not be feasible in some clinics, would be hard to cover different regions in the joint and subacromial space, could not provide direct information at the time of surgery, and has been reported to fail to detect a relationship between that and pain or disability in osteoarthritis [ 33].
For example, Google's computer vision system labeled African-Americans as gorillas, while Microsoft's vision system was reported to fail to recognize darker-skinned people.
Using dI-containing oligonucleotides, primer extension reactions with the wild-type enzyme were reported to fail [ 44, 59].
Interestingly, the reaction was reported to fail when using 2-methylalanine ethyl ester presumably because of the steric hindrance at the nitrogen.
The current findings suggest that CT with metal artifact reduction is a better tool in assessing periprosthetic acetabular osteolysis in MoM THA and to screen implants which are reported to fail secondary to periacetabular osteolysis.
The degree of this epigenetic change seems to be of predictive value, since tumors with incomplete MGMT promoter methylation are reported to fail on temozolomide, while those with complete methylation show a significant trend to respond to this treatment [ 65].
