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It has been reported that small pore sizes can limit cell migration and colonization [ 25, 26], vascular ingrowth, and nutrient and water transfer [ 27].
It has already been reported that small primary tumours could lead to metastasis in different cancer types (Menz et al, 1985; Sho et al, 1998; Chiang et al, 2008).
Indeed, it has been reported that small molecule inhibitors specific to FAK tyrosine kinases have both in vitro and in vivo efficacy in interfering with mammary tumour progression [ 30, 31].
Considering antiparasitic drugs after surgery, it has been reported that small cysts, not removed by surgery, can be missed by magnetic resonance imaging and cause further complications in an already tenuous post-neurosurgical patient.
It has been reported that small amounts of the cysteine desulfurase NFS1 and its binding partner ISD11 are expressed in the cytosolic and/or nuclear compartments of mammalian cells (Land and Rouault, 1998; Shi et al., 2009), where small amounts of the scaffold proteins ISCU and NFU1 are also present (Tong et al., 2003; Tong and Rouault, 2006).
It has been reported that small quantities of uromodulin/THP can be detected in blood using sensitive immunoassays [ 29, 30], but it is possible that some proteins in the serum simply cross-react with the antibody raised against the uromodulin/THP proteins [ 31].
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For example, it has been reported that smaller, hydrophilic peptides (e.g., leptin, 16 kDa) can be widely distributed throughout the CNS upon ICV delivery whereas larger polypeptides (e.g., FGF-2, 22 kDa; GDNF, 24 kDa) which also have an affinity for components (e.g., heparan sulfate) of the extracellular matrix have a more limited distribution [26], [27].
It was reported that small ZrO2 grains crystallized usually in tetragonal and/or cubic phase [39].
It was reported that small amount of water (few %) significantly decreases anode polarization resistance, while its too large amount can degrade anode performance especially at high electrical load and low H2 concentrations in the fuel [6].
It was reported that small Rho GTPases, including Cdc42, are activated and play a role during invasion, but the involved signaling cascades remained unknown.
Recently, it was reported that small molecules could bind to the ATPase domain of GRP78/BiP and facilitate dissociation of BiP complexes with other proteins.
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been reported that reduced
been evidenced that small
been assumed that small
been argued that small
been anticipated that small
been raised that small
been found that small
been reported that cortical
been thought that small
been proposed that small
been reported that other
been hypothesized that small
been reported that original
been recognized that small
been known that small
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com