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It has been reported that normal circulating lymphocytes including CD4-, 8-, 56-positive cells expressed P-gp 29.
It has previously been reported that normal cells undergo withdrawal from the cell cycle during nutrient or glucose deprivation rather than undergo cell death (Shim et al, 1998).
It has been reported that normal breast tissue is much less likely to be ER-positive in Japanese women than in US women 14, 55.
Regarding cell growth inhibition, it has been reported that normal melanocytes in culture are sensitive to the growth-inhibitory effects of TGFβ, whereas melanoma cell lines demonstrate various degrees of resistance to these effects [ 14, 15].
It has been reported that normal pancreatic islet cells and pancreatic neuroendocrine tumors showed positive reactivity for the progesterone receptor [ 49], and our literature survey demonstrated that epithelioid cells showed a high positive rate for PP (89.7%, 70/78) immunohistochemically.
Similarly, it has been reported that normal aging of the motion segment and pathological degeneration cannot be distinguished at a histological level [ 13], suggesting that the biological process is the same in normal aging but is accelerated in the pathological state.
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It has been reported that the normal blood pH is 7.4, while tumor tissue is slightly acid [27].
It has been reported that the normal physiological serum levels of TNFα vary from 1 to 13 pg/ml [ 36- 39].
It has been reported that, during normal epidermal homeostasis, the IFE can be maintained by committed progenitors (Clayton et al., 2007).
Of potential in vivo relevance, it has been reported that morphologically normal tissue, adjacent to breast carcinomas, displays loss of heterozygosity similar to that displayed within the tumor tissue [ 53].
It has been reported that the normal mean portal vein diameter in Chinese populations is 9.5 ± 1.3 mm [ 18], while it is 11.0 ± 0.3 mm in French populations [ 19].
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