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However, it has also been reported that modification can activate a previously inactive compound [ 57].
It has been reported that modification of UCP2 could sensitize certain cancer cell for chemotherapy in leukaemia cells [ 21].
On the other hand, it has been reported that modification by phosphorus of the mesoporous material MCM-41 led to significant hydrothermal stabilization.
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cPCL showed endothermic peak at 47.65 °C, which was lower than the reported melting point of PCL (60 °C) It has been reported that modifications in polymer or polymer structure will change its melting point (Orozco-Castellanos et al. 2011).
- Moreover, it has been reported that modifications in the DNA methylome can alter polycomb binding and repressive pattern.
It has been reported that modifications of PL composition influence a range of cellular processes (Holzer et al., 2011; Pinot et al., 2014).
Indeed, it was reported that modification or transformation of the aromatic ring of ZEN resulted in a remarkably decreased estrogenic activity compared to non-transformed ZEN (Drzymala et al. 2015).
It was not an unexpected result, as it was reported that modification in the lignin biosynthesis pathway may cause increase in cellulose level.
Several modifications and variables have been reported that could affect the generation of the phenomenon.
Also, it is reported that modifications of the glycan structures are associated with several diseases as well.
It has been reported that histone modifications, such as H3K9me2, were associated with decreased MLH1 mRNA expression [ 28– 30].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com