KRT6A is a member of the cytokeratin gene family, and recently it was reported that ectopic SOX2 over-expression up-regulated the KRT6A mRNA level in a lung adenocarcinoma cell line [17].
It has been reported that antisense TM29 (a SEPALLATA homolog) tomato mutants also exhibits ectopic shoot growth from fruit but these mutants have different flower morphology [27].
It has been reported that the 35S::PI A. thaliana also modifies sepals into petaloid organs but no ectopic stamen is formed (Krizek and Meyerowitz 1996; Lamb and Irish 2003; Yang et al. 2003).
Hochedlinger et al. reported that ectopic OCT4 expression in somatic cells causes epithelial dysplasia.
It is reported that knocking down or ectopic expression of Sema5B both change the trajectory of CT axons along the new border where Sema5B expresses (Lett et al., 2009).
86,94,96,97 Indeed in Enam null −/− mice it was reported that there was no true enamel, ectopic amelogenin secretion and ectopic mineralisation.
It was reported that in erm - mutants, dedifferentiated neuroblasts can establish ectopic type II neuroblast lineages and form ectopic glial chambers (Weng et al., 2010).
Abnormal expression of MUC5B in distal airway epithelial cells of IPF lungs has been reported, suggesting that ectopic expression of MUC5B also plays a role in the development of IPF (Plantier et al., 2011).
However, it has been previously reported that ectopic expression of C/EBPα is unable to induce adipogenesis in a PPARγ null background [37], although in contrast, PPARγ restores adipocitic potential in C/EBPα null fibroblast [38].
