Sentence examples for been reported that destabilization from inspiring English sources
Indeed, it has been reported that destabilization of MT activates ERα transcriptional activity, whereas stabilization of MT represses ERα transactivation [9].
In most of the studies, the modes of action of APPs have also been reported that include destabilization of the plasma membrane of parasite and inhibition of internal targets.
It has also been reported that membrane destabilization is essential for fusion (Ryan et al. 2005 and Domingues et al. 2009), and that peptides and proteins forming hydrophobic or hydrophilic cationic clusters show membrane-fusion activity (Cummings and Vanderlick 2007; Niidome et al. 2000; Fujii et al. 1993; Abu-Ghazaleh et al. 1992).
It has been reported that oxidative damage to SOD1 results in their dissociation into monomers and monomer destabilization, and aggregation in vitro [40].
Interestingly, it has also been reported that PAN3 depletion causes a reduction in P-body number concomitant with a destabilization of ARE-containing transcripts [ 18].
Furthermore, it has been reported that more than a third of those translationally repressed target genes always displayed detectable mRNA destabilization [ 14].
For example [ 39] it has been reported that the increased exposure of hydrophobic residues and the reduction of solvent exposed charged amino acids determines a destabilization of the protein surface.
It is reported that one mechanism of the inactivation of pRb by E7 is the targeted destabilization of pRb [11], [12], [36], [37], [38].
Surfactin is an amphipathic molecule that has been reported as a plasma membrane destabilization agent, thus disturbing its integrity (Sánchez et al. [2010]).
Recently protective effects of axonal taxol have been reported in neurons exposed to 3 hours glutamate, strengthening our current results and suggesting that microtubule destabilization is an early and upstream event in axon degeneration following excitotoxicity [ 41].
Interactions between E6 and fibulin-1 have also been reported to support cellular transformation and tumor invasion by further contributing to the destabilization of the ECM [ 31].
