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Overexpression of ST3GAL-1 has been reported in types of tumors like colon and breast cancers [ 10, 17].
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Low concentrations of insulin-like growth factor-I (IGFI) have been reported in type 1 diabetes mellitus (T1DM), suggested to be due to low insulin concentrations in the portal vein.
This has occasionally been reported in type V OI, especially in males and in the femur [18, 19, 20].
These are usually encountered in children with OI receiving biphosphonates, but have been reported in type V OI independently of any treatment.
However, increased TGF-beta1 levels have also been reported in type 2 diabetes.
Altered numbers of blood DCs have been reported in type 1 diabetes (T1D).
All of these have also been reported in type 2 diabetes (6, 7).
IMAT accumulation has also been reported in type II diabetes, aged muscles, denervation, and in chronic disuse-induced muscle atrophy.
A significant increase in CVD mortality related to increasing HbA1c levels has been reported in type 1 diabetes [ 4].
Previously, a similar citrulline-independent ACPA response has been reported in type 1 autoimmune hepatitis, AIH-1 [ 7].
Reduction of size of both intracardiac ganglia and intracardiac neurons has been reported in type 1 diabetic mice [ 16, 18].
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