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High rates of attrition have been reported in randomized controlled trials of patients with severe psychiatric illness, including psychotic depression (MDpsy).
Modest improvements in psoriasis have been reported in randomized, double-blind, controlled studies of sulfasalazine [ 138, 140].
To date, the use of biologic therapies in patients with early PsA has not been reported in randomized controlled trial, or from real clinical practice.
Reductions in diabetes incidence of 42 58% in lifestyle modification groups compared with control groups have been reported in randomized controlled studies of individuals with impaired glucose tolerance (IGT) (1– 3).
These recovery rates need to be considered in the context of what we know about natural recovery in depression and the anxiety disorders and also the clinical outcomes that have been reported in randomized controlled trials of CBT.
The numbers of adverse events related to seizures in the RNS System trial was not higher than what has been reported in randomized controlled trials of antiepileptic medications approved by the U.S. Food and Drug Administration FDAA) for adjunctive treatment of partial-onset seizures.
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Before the publication of the PRIMA study results, the clinical benefit of R-maintenance was reported in randomized studies including patients with recurrent or resistant FL who were treated with chemotherapy or chemoimmunotherapy.
However, the effect of bisphosphonates on improving QOL in osteoporotic patients has not been reported in a randomized controlled study in Japan to date.
Similar results have been reported in other randomized controlled trials comparing GA to regional anesthesia in the elderly[ 41] as well as observational studies[ 39].
The benefit of using HIPEC as an adjuvant treatment for advanced gastric cancer has been reported in several randomized studies and two meta-analyses [ 38, 39].
The benefit of using HIPEC as an adjuvant treatment for advanced gastric cancer has been reported in several randomized studies and a meta-analysis [ 38].
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