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Elevated hepatic stiffness has been reported clinically with increases in hepatic venous pressure gradient (HVPG).
Haematological toxicities have been reported clinically with PARPi, particularly when administered with cytotoxic drugs (Do and Chen, 2013).
Importantly, comparable effects have been reported clinically, with the GLP-1R agonist, liraglutide, decreasing circulating levels of the inflammatory macrophage activation molecule, sCD163, in diabetic patients [ 17].
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Sedation has been reported clinically in man treated with regular therapeutic (or higher) doses of metoclopramide [ 1, 11, 12].
Less common duplications of paternal origin have been reported in clinically asymptomatic individuals [ 10, 21– 24], individuals with clinical symptoms but without the ASD phenotype [ 20, 23, 25] and subjects with clinical alterations and ASD phenotypes [ 20, 26].
Clinically significant weight gain has been reported during treatment with atypical antipsychotics.
Clinically, noise assessment of dental procedures has been reported with regard to hospital occupational health [ 7].
However, statins have not been reported to be associated with clinically significant coagulopathy in patients with trauma.
However, it has been reported that some patients clinically diagnosed with human cerebral malaria had little or no IRBC sequestered in their brain capillaries [11], [12], suggesting that IRBC sequestration might not be sufficient per se to cause CM.
Biguanide (metformin), statins and NSAIDs (aspirin) have been reported to be associated with a clinically reduced EC incidence [ 6, 19] and have an anti-tumor effect in EC cells [ 20- 22].
The incidence of clinically significant DVT has been reported from 0.33 to 40 % with fatal PE 0.04 0.22 % in hip and knee arthroplasty [1, 2, 5, 6].
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