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Both missense point mutations and large extracellular domain deletions (EGFRvIII, which due to alternative splicing misses exon 2 7) affecting the EGFR gene have been reported at considerable frequency in GBM and result in constitutive activation of the receptor and of the underlying PI3K pathway [12].
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In contrast to the experiences of similar "blocks" at Christmas and New Year, the deliveries of Monday were kept, generally, very punctual, no considerable delay having been reported at head-quarters.
Unusually high tides were reported at St . Johns Florida, causing considerable damage to wharves and freight between September 15 and September 18, long after the storm moved offshore the Southeastern United States.
4 Nationally, uptake is reported at around 50% with considerable variability.
Flooding was reported at New Bern.
However, no previous experimental study on steel silo transition junctions has been reported due to the considerable difficulties associated with testing these thin-shell junctions at model scale.
Finally, it has been reported that following ischemia/reperfusion at retinal level, a considerable increase of lipid peroxidation occurs.
Considerable progress has been reported in the field of TLRs.
Considerable pain reduction has been reported by others [ 2, 12].
Considerable socioeconomic and health inequalities have been reported in China.
I remember one man saying, 'You're driving my wife insane.' " This is reported with considerable relish.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com