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Moreover, the interaction between PCB and MeHg cannot be considered conclusive until it has been replicated in subsequent investigations.
While this has not been replicated in subsequent studies, as SEMA5A is important in axon guidance, they examined SNPs in other genes in this pathway to attempt to utilize these SNPs to predict outcome in patients.
As long as 45 years ago, Stubbs [7] noted that children with autism had altered responses to T cell mitogens, such as phytohemagglutinin or pokeweed antigen and these findings have been replicated in subsequent studies [8] [10].
Similar changes in LBM and FM have been replicated in subsequent studies using 1% Testim.
Some candidate-gene studies have provided promising leads (53– 57), but few associations have been replicated in subsequent efforts (58).
However, the findings have not been replicated in subsequent randomised clinical trials, and thus enthusiasm for aPC has declined.
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The formula could not be replicated in subsequent years.
The decline effect refers to the situation whereby an initially positive set of research findings concerning a phenomenon fail to be replicated in subsequent studies.
Generally, results of secondary measures need to be replicated in subsequent studies before being used to direct clinical decision-making, but such results can act as a clinical guide.
A GWAS produces many trait-SNP associations with low p-values, but few are replicated in subsequent studies.
Most of the results, however, could not be replicated in subsequent studies in other populations.
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