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Thus, the present results should be interpreted with caution until these findings have been replicated in larger samples.
[38] However, this association has not been replicated in larger patient cohorts of different ethnic origin and the phenotypic consequences are unknown so far.
79 This has since been replicated in larger cohorts.
More recently, these findings have been replicated in larger RA cohorts from different centers [ 28- 30].
These results have not yet been replicated in larger studies [ 63– 63].
However, these studies were small, noncontrolled and their findings have not been replicated in larger randomised controlled studies.
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Their small, localized successes have not yet been replicated in large populations.
These findings have been replicated in large observational studies [ 85, 86], confirming the trial findings and cost effectiveness [ 87] of IV rtPA in clinical practice.
This highly correlated 2-factor model has also been replicated in large samples of substance abusers (r =.81) and adult outpatients (r =.75).
These loci including 6q23, TRAF1/C5, STAT4, IL2RB, KIF5A, PRKCQ, IL2/IL21, CD226, CCL21, CD40, CTLA4 and IL2RA, defined by single nucleotide polymorphisms (SNPs), have subsequently been replicated in large independent panels of patients and healthy controls.
The discovery, presented by scientists at the annual meeting of the American Academy of Neurology in San Diego, still needs to be replicated in larger studies.
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