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The key observations including the lowering of Htt, the epistasis between Gpr52 and Rabgap1l and the phenotypic rescue have been replicated by multiple independent investigators.
Two additional genes, NALP1 (now NLRP1; NLR family, pyrin domain containing 1) and XBP1 (X-box binding protein 1), were first mapped by unbiased genome-wide linkage analyses and subsequently were identified by positionally targeted genetic association studies [ 7, 8]; both of these genes have subsequently been replicated by multiple studies [ 3, 6].
Other than in dementia of the Alzheimer type in which many of the identified susceptibility genes and even of loci identified in GWA studies have been replicated by multiple studies with large sample sizes (Paulson and Igo, 2011), the genetic architecture of vascular dementia and its subtypes is less well explored.
Similar(56)
This indicates that the BU-1 locus is either passively replicated equally from the left or from the right, or that is replicated by multiple, synchronous internal initiations (Guilbaud et al., 2011).
These results initially were replicated by multiple independent efforts (Drgon et al. 2006; Fehr et al. 2003; Lappalainen et al. 2005; Soyka et al. 2008); however, other investigators could not replicate the findings (e.g., Lind et al. 2008).
That can't be replicated by technology.
The model they're creating could be replicated by others".
The study was replicated by other labs, with similar results.
This was replicated by four individuals.
Any technology that can be replicated will always be replicated by someone else doing it cheaper.
This model can be replicated by countries facing similar challenges.
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