Sentence examples for been recognized that specific from inspiring English sources

However, it has been recognized that specific genetic backgrounds do affect the clinical outcome of patients with oligodendroglial tumors.

Several molecular alterations have been proposed to support tumor resistance to cytotoxic drugs, such as the expression of MDR phenotype, mutation of p53, bcl2 overexpression [ 3- 5], but only very recently it has been recognized that specific molecular or biological profiles might characterize tumor sensitivity to classes of agents with different mechanisms of action.

Although reasonable control and diagnostic parameters are utilized by each boiling water reactor (BWR) and pressurized water reactor (PWR) owner, it is recognized that specific values are not shared among everyone involved.

Nevertheless, it is recognized that specific targeting of GSC antigens during T cell induction may yield distinct findings.

It has long been recognized that the specific cellular response to TGF-β1 is context dependent and varies according to the cell type, the cellular environment and the activity of other signaling pathways [3].

More recently it has been recognized that allele-specific expression is relatively common among non-imprinted autosomal genes [ 91, 93, 97- 99] and that this difference in allelic expression is heritable [ 93].

More recently, it has been recognized that Malagasy carry specific point mutation variants (mtDNA nucleotides 1473 and 3423), which together have been termed the Malagasy motif [ 23].

It has been recognized that conventional project-specific consent for research using DNA databanks would render such research impracticable [ 16].

It has been recognized that genetic mutations in specific nucleotides may give rise to cancer via the alteration of signaling pathways.

Recently, it has been recognized that cannabinoids also have specific anti-tumor activity by inducing selective cell death in many types of cancer cells but not in the normal counterparts.

Even though it has long been recognized that substitution patterns are site-specific and depend on protein family, it is in general very difficult to estimate site-specific and family-specific substitution matrices due to a lack-of-data problem.