Sentence examples for been recognized that certain from inspiring English sources

Increasingly, it has been recognized that certain life-saving cancer treatments have gonadotoxic effects in cancer survivors [ 9- 12].

It has long been recognized that certain individuals with NTDs are born with malformed kidneys, and recent studies have discovered VANGL mutations in some NTD patients.

It was beginning to be recognized that certain rock sequences in the Catskill Mountains of eastern New York state in North America resembled the Old Red Sandstone of western England.

Although it is well known that sulfur acts as a poison for many nickel catalyzed reactions, it is now being recognized that certain benefits can be derived from following a partial and well controlled sulfidation treatment of the metal.

First, it was recognized that certain small molecules could inhibit the activity of protein kinases [ 23].

It is recognized that certain HLA allele combinations are common in certain populations, presumably due to linkage disequilibrium [ 35].

It is recognized that certain patients in poor prognostic groups can benefit from preoperative neoadjuvant therapy[ 13].

Although it is recognized that certain types of research, such as psychosocial studies, lend themselves to more creative forms of engagement, it must also be appreciated that there is always scope for user involvement.

It is recognized that certain therapeutic applications may benefit from optimizations of the antibody format, and this is sprouting an extensive line of research focusing on engineering for enhanced effector function, controlling of half-life, increasing stability and improving tumor and tissue penetration (extensively reviewed in [ 68]).

Recently, it has been recognized that endogenous intracellular lipids activate certain nuclear hormone receptors (i.e., PPARs, LXR and FXR). 10 Whereas PPARs are activated by fatty acids and their metabolic products, LXRs are activated by certain oxysterol metabolites of cholesterol while farnesoid-X receptor (FXR), which is not expressed in keratinocytes, is activated by bile acids.

11, 19, 20, 21 Although it has been recognized that the antibody response toward a certain lipid or the combination of lipids could be applied as biomarker, accurate assays, and large‐scale clinical analysis are lacking.