Of these, only L. monocytogenes and L. ivanovii are recognized as pathogenic for warm-blooded hosts.
It is possible that there are additional examples of pathogenic variation that is modeled in macaques or human variation that simply has yet to be recognized as pathogenic due to the vagaries of human research.
Genome-wide association studies have linked multiple regions to autism, and the role of genetic alterations within several genes for example, SHANK3, NRXN1, NLGN3, NLGN4X and CNTNAP2 [ 4, 5] is recognized as pathogenic.
Entamoeba histolytica is a pathogenic ameba that has recently been recognized as an emerging pathogen in men who have sex with men (MSM) in Asia-Pacific countries where it is not endemic, i.e., Japan, Taiwan, and Republic of Korea.
However, they have been recognized as important human pathogens, often acting as opportunistic pathogens in immunocompromised or severely-ill patients with symptoms compatible with bacteremia and without presence of other pathogenic organism [ 1- 3, 8].
Pathogenic E. coli has been recognized as the zoonotic agents responsible for a wide spectrum of infectious diseases (e.g., diarrhea, sepsis, and meningitis)[2], [3], [4], [5].
The oxidative stress has been recognized as a major component in the chain of pathogenic events that cause late complications in diabetes mellitus [ 25].
3-Oxo-acyl-acyl carrier protein (ACP) reductase (FabG) plays a key role in the bacterial fatty acid synthesis II system in pathogenic microorganisms, which has been recognized as a potential drug target.
Staphylococcus aureus is a common facultative pathogenic bacterium that has long been recognized as a burden in both human and veterinary medicine.
Some avian A/H5 and A/H7 strains of influenza virus are recognized as highly pathogenic (HP) in domestic poultry and concerns arise that this phenotype may carry over to infections of humans.
