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Novel benzimidazol-2-one non-nucleoside reverse transcriptase inhibitors (NNRTIs) have been recently identified, through rational structure-based molecular modeling and docking approaches, as highly effective inhibitors of the wild type and drug-resistant HIV-1 reverse transcriptase (RT).
Interestingly, connections between LD-associated proteins and NAFLD have been recently identified through genome-wide association studies (GWAS) as well as genomic and proteomic studies (Zhang et al., 2017).
Many putative proteases have been recently identified through genomic approaches, leading to a surge in global profiling attempts to characterize their function.
Mutations in the XRCC4 gene have been recently identified through whole-exome sequencing (WES).
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The same region was recently identified through linkage analysis of prostate cancer, followed by fine-mapping.
But Kuchma in turn has been weakened by the "Tapegate" scandal, involving secret audiotapes that purport to capture him ordering the disappearance of a journalist whose headless corpse was recently identified through DNA testing.
The presence of IL-17A mRNA in human glioma was recently identified through a large scale microarray analysis of Th1-, Th2- and Th17-related genes [23].
Solute carrier family 25 member 38 (SLC25A38) was recently identified through the positional cloning of a gene implicated in nonsyndromic congenital sideroblastic anemia [ 21].
Notably, 1,156 of these DMRs overlapped with the variably methylated regions that were recently identified through a comprehensive analysis of 42 human methylomes [ 26].
In two enhancer regions of the MyoD gene, the Distal Regulatory Regions (DRR) and the Core Enhancer (CE), two enhancer-associated lncRNAs, DRRRNA and CERNA, were recently identified through a series of ChIP-seq experiments [ 148].
The small-molecule probe STF-31 was recently identified through phenotypic high-throughput screening for its ability to kill renal cell carcinoma cells deficient in the Von Hippel-Lindau tumor suppressor gene (VHL) relative to cells in which the gene had been reintroduced.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com