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B6 ES cell lines have been available since the early 1990s [7], [8], [9]; however, in spite of the clear advantages of the inbred background few targeted mutations have been published compared to the widely used 129 ES cell lines [1].
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The results consistently show that positive studies are more likely to be published compared to negative studies.
There are concerns that studies with statistically significant results are more likely to be published compared to studies with non significant (negative) results.
If present, we would expect studies with moderate to low quality not showing an association between exposure and outcome to a lesser extent were published compared to studies showing an association.
A number of studies have been published comparing venlafaxine to SSRIs, however, and these have tended to favor the SNRI, but only by small margins.
6 Treatment is challenging; there is no universally accepted "gold standard" and although a small trial has been published, comparing infliximab to placebo, no randomized controlled trials have been performed for the usual systemic therapies.
Intermediate morphological, physiological, and performance traits have been reported for hybrids but little information has been published comparing the behavior of hybrids to the pure species.
Few studies have been published comparing high-intensity ASSR results to behavioral tests in the pediatric population [ 13, 22].
Publication bias refers to the fact that studies with positive results are more likely to be published compared with studies with negative results (Egger and Smith, 1998).
Basic science abstracts were more likely to be published compared with clinical abstracts.
Abstracts reporting positive results had a significantly higher probability of being published in full, while abstracts reporting null or negative results were half as likely to be published compared with positive ones (Table 3).
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CEO of Professional Science Editing for Scientists @ prosciediting.com