Sentence examples for been proven active from inspiring English sources

Our recently designed A199S/F227A/S287G/A328 W/Y332G mutant of human BChE has a considerably improved catalytic efficiency against -cocaine and has been proven active in vivo.

Our more recently designed A199S/F227A/S287G/A328W/Y332G mutant of human BChE, denoted as cocaine hydrolase-3 (Cochas, has a considerably improved catalytic efficiency against cocaine and has been proven active in blocking cocaine-induced toxicity and physiological effects.

Trehalose has been proved active against aggregation of polyQ-expanded huntingtin (43, 44), beta-amyloid (36, 42, 56), polyA-binding protein nuclear 1 (PABPN1) (45), the pathological prion protein (46), the amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD -associated protein TDP-43 (57), mutant synuclein (47) and also on the ARpolyQ (37).

The purified scFv was proven active and showed specific binding to HTNV GP antigen and then could be internalized into HTNV-infected cells.

Until BPA is proven active at environmentally relevant concentrations (the low nanomolar range), it is not certain that it poses risks to human health.

The generality of this enzymatic mechanism for cleavage of recalcitrant polysaccharides was recently shown for a CBM33 member (CelS2) that was proven active on cellulose (Forsberg et al. 2011).

This is expected as the CMV promoter which drives the NTRK1 gene in the plasmid has been proven highly active in neurons [ 34].

It has been proven that staying active and indulging in physical activity releases endorphins - the happy hormones.

The bovine PL10, albeit pseudogenized during the evolution, has also been proven to be active transcriptionally and may be involved in the regulatory coordination of bovine spermatogenesis [ 14].

The cytosine arabinoside analogue 2′,2′-difluorodeoxycytidine (gemcitabine) has been proven to be active in the treatment of pancreatic cancer (Abbruzzese, 2002a) with significant clinical benefit, but still with marginal survival advantage (El Rayes et al, 2003).

This very large activity improvement was due to the introduction of Co which has been proven to be very active metal in the DRM reaction.