Sentence examples for been proved active from inspiring English sources
Trehalose has been proved active against aggregation of polyQ-expanded huntingtin (43, 44), beta-amyloid (36, 42, 56), polyA-binding protein nuclear 1 (PABPN1) (45), the pathological prion protein (46), the amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD -associated protein TDP-43 (57), mutant synuclein (47) and also on the ARpolyQ (37).
Our recently designed A199S/F227A/S287G/A328 W/Y332G mutant of human BChE has a considerably improved catalytic efficiency against -cocaine and has been proven active in vivo.
Our more recently designed A199S/F227A/S287G/A328W/Y332G mutant of human BChE, denoted as cocaine hydrolase-3 (Cochas, has a considerably improved catalytic efficiency against cocaine and has been proven active in blocking cocaine-induced toxicity and physiological effects.
The purified scFv was proven active and showed specific binding to HTNV GP antigen and then could be internalized into HTNV-infected cells.
Until BPA is proven active at environmentally relevant concentrations (the low nanomolar range), it is not certain that it poses risks to human health.
The generality of this enzymatic mechanism for cleavage of recalcitrant polysaccharides was recently shown for a CBM33 member (CelS2) that was proven active on cellulose (Forsberg et al. 2011).
Many antagonistic microorganisms have been proved to be active In vitro or in vivo.
AS1411 is a G-rich quadruplex oligodeoxynucleotide that binds specifically to nucleolin and has been proved as an active oligo-drug for tumor therapy.
More interestingly, the bovine PL10 has also been proved to be active at the transcription level even though it may lose protein-coding potential [ 14].
It has been proved to be active, but its combination with chemotherapy in patients with unresectable, locally advanced pancreatic cancer has not yet been shown to be successful in a phase II trial by Silenseed Ltd [36].
These methods have been proved effective in increasing active hot spots along the Ag nanowire's longitudinal axis.
