The interplay between H3K36 acetylation and methylation has previously been proposed to regulate gene expression19.
Phosphorylation of FGF-1 at serine 116 (S116) has been proposed to regulate intracrine signaling.
Indeed, and in agreement with our results, the ERK5/MEF2 pathway has been proposed to regulate the expression of several ABC transporters, among which ABCG256.
Multiple mechanisms have been proposed to regulate ATP release with connexin (Cx) hemichannels and pannexin (Panx) channels receiving major focus.
A gastrointestinal renal kaliuretic signaling axis has been proposed to regulate potassium excretion in response to acute potassium ingestion independent of the extracellular potassium concentration and aldosterone.
This lid has been proposed to regulate product dissociation in the latter, while the side-chain of Tyr238 might exert a similar role in RgDAAO.
So far, dysregulation of miR-17 has been mainly investigated in the context of cancer38,39, but has also been proposed to regulate IL-10 in regulatory T cells40.
Sympathetic nerve input has been proposed to regulate cardiac growth and differentiation.
Based on data from in vitro tissue explant and ex vivo cell/bead implantation experiments, Bmp and Fgf signaling have been proposed to regulate hepatic specification.
The microtubule association by Climp63 has been proposed to regulate the mobility of the translocon and, thus, may indirectly regulate the stability of the translocating complex.
Ca2+ has been proposed to regulate Na+ channels through the action of calmodulin (CaM) bound to an IQ motif or through direct binding to a paired EF hand motif in the Nav1 C terminus.
