Neurexins have been proposed to function as major mediators of the coordinated pre- and postsynaptic apposition.
Transient receptor potential canonical (TRPC) proteins have been proposed to function as plasma membrane Ca2+ channels activated by store depletion and/or by receptor stimulation.
BRI1-associated receptor kinase 1 (BAK1) is an LRR-RLK found in A. thaliana, which has been proposed to function as an adaptor protein that is required for the proper functioning of other RLKs.
Myosin Va has also been proposed to function in nuclear compartmentalization and transcription [47].
Two of these ion channels, termed TRPM8 and TRPA1, have been proposed to function as cold transducers [8], [9].
NuA4 is the only essential HAT complex in S.cerevisiae and has been proposed to function in DNA replication [58], [61].
The QKI isoforms have been proposed to function in alternative splicing in the myelin associated glycoprotein mRNA [16].
RhoH has also been proposed to function as a negative regulator of other Rho GTPases, particularly Rac.
HIF-1α and HIF-2α have been proposed to function as key factors in angiogenesis and their expression has been associated with VEGF expression in human melanoma [4].
Recently, galactinol has been proposed to function as a ROS scavenger under stress conditions such as chilling or high-irradiance [33].
Ro60 has been proposed to function as a scavenger for mis-folded RNAs in a quality control pathway for non-coding RNAs [13], [14], [15].
