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It has been proposed that persistent insulin resistance accelerates β-cell failure.
Blood vessels in DC nodules express high levels of basic fibroblast growth factor (bFGF) [ 10] and it has been proposed that persistent TGF-β signaling in conjunction with increased bFGF levels might be responsible for the increased proliferation and fibrosis taking place in DC [ 30].
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In the recently published EULAR recommendations for the management of early arthritis [ 16], a list of factors has been proposed that predict persistent and erosive disease.
While it has been proposed that transient and persistent currents both arise from Nav1.6 channels [33], [34], differences in channel gating and kinetic properties may have important functional consequences.
It has been proposed that a condition of persistent inflammation may promote the activation of the mesothelium lining the body cavities.
Observational and empiric studies of coughing after pulmonary resection (CAP) have been conducted, and it has been proposed that some cases of persistent CAP are caused by acid regurgitation [ 2].
As an example, it has been proposed that many pathogens responsible for persistent chronic infections highjack immunological regulatory mechanisms [ 32].
It has been proposed that birth weight has a persistent and independent effect on cancer risk in adulthood [ 1– 17].
It has been proposed that the bolus of ovarian hormones during pregnancy initiates persistent systemic changes in the parous individual.
It has been proposed that in aging, a vicious cycle can occur in which increased oxidative stress leads to persistent mitochondrial dysfunction and severe energy depletion [9], [10].
As duration of super-shedding is unknown, Carlson et al. [ 2] proposed that persistent low-level shedders of E. coli O157 H7 were a greater food safety risk than were intermittent super-shedders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com