These short-cuts cannot be properly validated for the time being, due to the paucity of identified low-penetrance risk modifiers.
When possible, oligonucleotides are designed so that they might also be used with more than one subtype; however, screening for resistance in non-B subtypes requires that the oligonucleotides are properly validated for those subtypes.
At the time of study design in 2009, an instrument to measure quality of life in diabetic patients that was properly validated for Spain was sought.
This is the first study in which the HRM method has been properly validated as a scanning method for EGFR and KRAS mutations in a large sample set showing accurate mutation detection with 100% sensitivity.
The factor V Leiden mutation test should be performed using any of the accepted technical approaches as long as they have been properly validated by the laboratory, while adhering to current ACMG/CAP quality assurance guidelines for molecular genetic testing.
Surge capacity for testing at the federal, state, and local levels should be identified, and an adequate supply of reagents that have been properly validated and checked for quality should be ensured.
At the time of this study, screening tools for males had not been properly validated and the efficacy of ED screening and the true prevalence remain unknown [17, 24].
None of the currently used clinical severity indices for patients with IBD have been properly validated.
None of the currently used clinical severity indices for patients with inflammatory bowel disease (IBD) have been properly validated.
10 11 However, none of them have been properly validated.
Nevertheless, diagnostic accuracy for both exacerbation presence as well as severity categories has never been properly validated.
