Since inhibition of the chaperone activity of lens crystallins is primarily shown to be responsible for the ease and specificity with which redADan manifests appearance of cataract in lens organ culture, we also studied the effect of redADan on another chaperone.
Still, be it opera or dance, there will always be limitations in bringing a show that's been primarily designed for a stage to the screen.
The defensive features, however, were primarily for show, possibly to provide a backdrop for jousting between the two-halves of the Order of the Garter.
Alzheimer's disease is the most prevalent form of dementia (loss of intellectual function), and treatment had been primarily supportive until drugs that show modest promise for improving cognition (tacrine) were developed.
In light of the reported selectivity of this chemical scaffold towards EHMT1/2, the library was primarily examined for compounds showing additional EZH2 inhibitory activity, as defined by re-expression of KRT17 and FBXO32, genes which are known to be silenced in an EZH2 dependent manner [ 30].
In this regard, NKp30, one of the three natural cytotoxicity receptors, has been shown to be primarily responsible for the NK cell mediated killing of autologous iDCs [28].
In the mouse, a subset of lymphoid-resident CD8α+ DC expressing the c-type lectin langerin (CD207) has been shown to be primarily responsible for cross-presentation and IL-12 production following injection of soluble antigen and adjuvant [18].
This particular amino acid substitution was shown to be primarily responsible for the functional effects of exon 6 splicing on Nav1.5 channel parameters.
In addition, the developed methods are primarily used for accountability purposes: showing impact to external funders, instead of learning how to better employ research and enhancing the realization of beneficial contributions.
Do you think these shows are primarily vehicles for corporations to sell the lifestyles which they highlight?
