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Some of these variables that have not been previously reported include the absence of headache (related with septicemia and meningitis rather than meningitis alone), bulging fontanelle, grunting and poor feeding on admission (physical signs encountered in infants), vomiting on admission and a positive blood culture or CSF gram stain.
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Thirteen of these genes had not been previously reported, including the important enzymes geraniol-10-hydroxylase (G10H), secologanin synthase (SCS), and strictosidine synthase (STR) (Table 2).
Only five cases have been previously reported, including a 28 month old boy [ 4], one child [ 1], one teenager [ 5], and two adults [ 2, 3].
Most of these predictors have been previously reported, including age [ 5, 14, 16, 20, 21], comorbidity [ 14, 16, 21] and illness severity [ 5, 6, 16, 18].
As suggested, we performed WISH to look at the expression of 3 additional wound-induced genes that have been previously reported, including egr-3, fos-1 and jun-1, which are homologs of the "immediate early genes".
Eight of the 13 differentially expressed ncRNAs were up-regulated following heat shock (ReCO6, ReC15, ReC20, ReC33, ReC55, ReC76, ReA01 and ReE02) and had been previously reported, including a well-characterised RNase P (ReC55).
Our data are in agreement with what has been previously reported including our own (Meissner et al, 2000; Xu et al, 2011), and similar to other cancer tissues (Ji et al, 2003; Lin et al, 2007; Ying et al, 2012).
Only 2 cases of human infection caused by this rickettsia had been previously reported, including infection in a patient returning to France from Morocco, and another in a patient in South Africa (9, 10 ).
Several zebrafish models associated with myeloid malignancies have been previously reported, including transgenic zebrafish that exhibit K-RASG12D, NUP98-HOXA9, Stat5 (H298R), Stat5 (NPM1F), NPM1, tel-jak2a, AML1-ETO, FLt3-ITD, FLT3-TKD (D835Y), MYCN, or MOZ/TIF2 expression.
The analyses used to estimate exposure were prospectively planned to include persistent and non-persistent chemicals in breast milk and placenta (EU grant QLK4-CT-2001-00269), moft of which have been previously reported, including OTCs from placentas but not from breast milk [ 29, 31- 38].
Several other farm-level risk factors have been previously reported, including the purchase of animals from herds with PRRSV, the use of semen for artificial insemination from infected boars, high herd size [ 7],[ 8], poor farm management practices (e.g. not isolating animals after purchase [ 7]), or the use of modified-live vaccines [ 8],[ 9].
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