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It has been previously recognized that amongst the huge number of descriptors, only a few are relevant for efficient model building [30].
Although it has been previously recognized that most transcripts are expressed at low abundances and highly abundant transcripts are rare, the fitted RAD in this study for the first time precisely described the constitution of transcriptomes.
It has been previously recognized that adult stem cell attrition may be a mechanism contributing to these disorders [ 20- 26].
It has been previously recognized that entropy-driven hydrophobic interactions generally result in a large Δ Tm,[ 17] and this may be driven in the present case by exposed hydrophobic patches in the PfMTIPΔ60 CTD.
It has been previously recognized that CD4 mimetics induce a short-lived activated Env state that deteriorates into an inactive Env form [ 2]; however, CD4 mimetics are usually not very potent in doing so.
Although it has been previously recognized that increased drag reduces speed when the propulsive force is constant, it has been difficult to confirm the effect of drag on swim speed using diving animals.
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It was previously recognized that structurally related domains used for different functions appear across the animal and plant kingdoms, since L-type carbohydrate-recognition domains are found in the legume lectins in plants as well as the sorting lectins such as ERGIC-53 and VIP36 in animal cells [ 24,27].
It was previously recognized that both OPN and BSP can each increase transcription, activation and functional localization of MMP-2 (Fedarko et al., 2004; Karadag and Fisher, 2006; Liu et al., 2004; Mi et al, 2006; Philip et al, 2001; Teti et al, 1998); however, the converse relationship has not been reported.
Our studies raise the question of whether these tissues exhibit finer grained regional patterns of gene expression than has been previously recognized, patterns that might be supported by small autonomous differences in their stem cells.
Particularly, some North American aDNA studies suggest that the founding migrants exhibited greater molecular diversity than what has been previously recognized, showing that during the Early-Middle Holocene there were more than five founding mtDNA lineages [46], [47].
To put it another way, Darwinius and Afradapis independently evolved traits that would later be seen in anthropoids through convergent evolution (a possibility that had been previously recognized years earlier when adapids were still considered contenders for anthropoid ancestors [Gingerich et al. 1994]).
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