In fact, LADs correspond in their properties to GC-poor isochores, which were previously localized at the periphery of the interphase nucleus (Saccone et al. 2002).
The turbot main SD region was previously localized at the proximal end of LG5, very close to SmaUSC-E30, between Sma-USC270 and Sma-USC65 (Martínez et al. 2009) (see Figure 1).
In addition, ERα and β have been previously localized to mitochondria in various tissues [ 32, 33].
Because RACK1 is an adaptor molecule that has been previously shown to localize at cell cell contacts to promote cell cell adhesion (Mourton et al., 2001) and to regulate membrane localization of diverse partners (Adams et al., 2011), we further investigated the xMELK and RACK1 relationship.
This plasmid contains 499 amino acids from the PutAMT1 1 ammonium transporter from P. tenuiflora, which has been previously demonstrated to be localized at the nucleus periphery in correspondence with the ER and the plasma membrane [ 17].
XPF-ERCC1 was previously shown to localize at telomeres (Zhu et al., 2003), and in this light we found that all of the XPF-ERCC1 foci in cells colocalize with SLX4.
ARF6 has been previously shown to co-localize with endocytic hTAC in the tubular endosome and regulate hTAC recycling.
It has been previously demonstrated that Rab5 localizes on macropinosomes [16], [22], [28].
It has been previously shown that a pool of VAMP7, localized at the plasma membrane, is internalized via Hrb (Human immunodeficiency virus Rev-binding protein) (Chaineau et al., 2008; Pryor et al., 2008).
ChIP-seq of γ-H2AX to localize DSBs has been previously performed.
