Many genes associated with glutamateric neurotransmission have been previously implicated in schizophrenia, including GRM3, GRIN2A, SRR and GRIA1 [16].
ben1 mutant has been previously implicated in pathogen response [10] and shows cell polarity, BFA sensitivity, and growth defects.
Interestingly, a number of pathways identified in the genetic predisposition lists (GP1 and GP2) have been previously implicated in this heterogeneous disease.
AMPK has been previously implicated in the regulation of glucose uptake (review in [24]).
Although FOXO1 has not been previously implicated in AD, an exception may exist.
Some of these molecules have been previously implicated in decisive developmental patterning of the nervous system.
A similar thalamic area on the left has been previously implicated in calculation [18].
Oxidative stress has been previously implicated in HF diet-induced obesity [63] [65].
Cerebellum is another area that has been previously implicated in many studies.
Moreover, for other highly methylated genes, loss due to epigenetic silencing has been previously implicated in aggressive tumor biology.
For example, KIT has been identified as a proto-oncogene, and has been previously implicated in glioblastoma [40] [42].
