Sentence examples for been previously described although from inspiring English sources

Such associations have not been previously described, although mTORC2 complex members and members of the CFTR chaperone machinery (Hsp70) have been shown to form part of the mTORC2 complex under heat shock stress33.

However, a direct relationship between growth factor signaling pathways and NFκB activation has not been previously described, although FGFs have been known to antagonize TNFα-induced apoptosis.

Blastula expression of these genes has not been previously described, although later expression has.

The importance of the IGF-IR pathway in treatments targeting PCSCs has not been previously described, although several recent reports have demonstrated an association of this receptor with cell stemness in some tumors [ 49, 50].

To our knowledge, such structures have not been previously described, although voids in the cell wall near the eyespot have been seen in conventional plastic sections (G Kreimer and S Geimer, personal communication, May 2014).

Similar lncRNA-dependent movements were previously described, although towards transcriptionally silent compartments [ 53, 54].

A mouse strain carrying a spontaneous point mutation in mouse Sod1 has been previously described (15), although the equivalent mutation in humans has not been identified as pathogenic.

However, within human breast tissue, the presence of CK14+ epithelial cells within the luminal layer have been previously described [ 33– 36], although the localization of CK14+ luminal cells was not evaluated with respect to lobule types.

The strengths and limitations of this data have been previously described [ 12], although research has demonstrated good correlation between ICD-9CM coded mental health disorder diagnoses and evidence of psychoactive pharmacotherapy [ 28], confirming the utility of surveillance databases in identifying functional psychiatric morbidity.

The proportionately greater under-representation of UpA dinucleotides for a given G+C content observed in mRNA sequences has been previously described [ 7], although this phenomenon extends to several other dinucleotides which show even greater compositional differences (such as GpA and CpA in human mRNA; Additional file 2: Figure S1B).

Upregulation of SDC1 has been previously described in breast cancer, although with values exceeding 10 times those of the normal tissue, as determined by immunohistochemical staining quantification [ 25].