Sentence examples for been postulated that mutant from inspiring English sources

However, it has been postulated that mutant SOD1 can indirectly interact with Derlin-1 via other ERAD components, such as p97, VIMP and E3 ligases (Nishitoh et al., 2008).

It has been postulated that selective inhibition of CHK2 could increase the efficacy of genotoxic cancer therapies in a p53 mutant background by modulating resistance pathways and may also be radioprotective to normal p53 wild-type tissues.

It has been postulated that specific sterols that are absent from, or are present at abnormally low levels in, the mutants and are required for appropriate signalling for cell division and expansion.

It has been postulated that 2-hydroxylated estradiol is anticarcinogenic.

It has been postulated that caspase-2 can directly injure mitochondria.

It had previously been postulated that the upregulation of cell cycle regulators, mainly Cyclin A, Cyclin E, and Cdc25, may be the reason for this occurrence in Pros mutant neuroblasts [ 35].

As we could not detect any meaningful transfer of the C186S and the C181S/C184S mutants, it can be postulated that B-to-T-cell transfer of Ras both at the IS (trogocytosis like) and via TNTs is linked to adequate membrane anchorage.

Accordingly, it was postulated that the neoR cassette sequence had interfered with the mutant allele expression, consequently restricting the dominant-negative effect of the mutation.

In conclusion, we showed that the P. putida KT2440 relA/spoT mutant is able to accumulate mcl-PHAs, therefore it could be postulated that the stringent response is not necessary for polyhydroxyalkanoates synthesis using oleic acid as an external carbon source.

It was postulated that Abl regulates Ena's location in cells because Ena is mislocalized in d-abl mutant flies [ 14].

It may be postulated that these models are simply measuring the relative death rates of the Phe/Phe and Phe/Tyr mutants, as compared to EF3030, and not actual survival and growth.