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It has also been postulated that melatonin might influence insulin secretion through a paracrine effect of glucagon [ 14].
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A third explanation, the 'melatonin hypothesis', was postulated that would explain lower risk for underground miners.
It has been postulated that HH may be the result of a chronobiological disorder, serotonin, and melatonin dysregulation or a disturbance of rapid eye movement (REM) sleep.
It has been postulated that 2-hydroxylated estradiol is anticarcinogenic.
It has been postulated that caspase-2 can directly injure mitochondria.
It has been postulated that alcohol may influence the risk of breast cancer through effects on pituitary-prolactin secretion, metabolism and clearance of Oestrogen by the liver, or pineal-melatonin production (Willett et al, 1989; Hiatt, 1990).
Weber found that height at age 18 is dependent on month of birth using an Austrian male cohort and postulated that melatonin may play a role in growth [ 35].
10 12 In sum, it is postulated that exposure to light at night during shift work suppresses melatonin production leading to increases in sex hormones, which may in turn increase breast cancer risk.
It is postulated that PACAP is involved in nociception.
It's postulated that this activity resets the overactive pain-generating areas in brain.
Bentkowski et al. [ 17] postulated that melatonin might act as a stress signal inhibitor, since they found that addition of melatonin resulted in disturbed behavioral response of D. magna to kairomones released by a vertebrate predator, i.e. fish.
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