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It has been postulated that formation of iodolipids such as iodolactones or iodoaldehydes represents a form of thyroidal autoregulation [ 26], which may be the mode of action of iodide inhibition of thyroid function in the Wolff Chaikoff effect [ 27- 29].
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Since this same hinge is observed between the different CnA-CBD complexes, it can be postulated that formation of the complex mainly involves bending at a single site on CaM, and that the bending is not constant in the complex, but significant flexibility exists also in the crystal state.
While the exact mechanism of its toxicity remains unknown, it has been postulated that the formation of toxic reactive metabolites (RMs) may play an important role in the hepatotoxicity of TGZ.
It has been postulated that coordination complex formation of 111In with acetate buffers is necessary for efficient labelling of DTPA- and DOTA-conjugated compounds [13] since it is assumed that the coordination complex formation prevents the formation of insoluble 111In-hydroxide.
In this perspective, it had been postulated that CD44/MMP-9 CD44/MMP-9rmation on the complexrformationt signify as a nonel motheity-enhancell surfacefor tumightellsignify eventuasly contributes their invasivenovel
It has been postulated that blood island formation results from in situ differentiation of progenitor cells.
It has been postulated that reciprocal asymmetric dimer formation, i.e. the acceptor kinase becomes the activator and vice versa leads to the full activation of both monomers [ 14].
It has been postulated that severe hypoxia may induce the formation of new tumour blood vessels necessary for further tumour growth (Folkman, 1995).
It has been postulated that dysregulated function of HDACs leads to cancer formation and development [ 11].
Additionally, it has been postulated that one mechanism by which caffeine alters bone formation and growth is by affecting mesenchymal stem cells and osteoblasts [ 20, 21].
10 12 Thus, it has been postulated that TNF inhibits and TNF blockade stimulates new bone formation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com