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Although it has been postulated that excessive BDNF is deteriorating for neuronal survival or neurite outgrowth, further investigations are needed to clarify the mechanism of paradoxical lack of increase in BDNF levels in the mouse brain.
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It is postulated that excessive accumulation of hypoxic induced factor (HIF) in the neoplastic stromal cells of RCH leads to the production of other angiogenic factors that are able to maintain and promote the growth of primary hemangiomas [ 6].
It has been postulated that 2-hydroxylated estradiol is anticarcinogenic.
It has been postulated that caspase-2 can directly injure mitochondria.
It has been postulated that bisphosphonates may affect healing if given soon after a fracture.
The decline in goblet cell numbers observed with Gram-negative strains was accompanied by a significant increase in mucin secretion, thus it was postulated that these were related: excessive mucin production exhausted the cells and caused changes in the architecture of the epithelial layer (restored by bifidobacteria).
Soon after the discovery that cathepsin K was a major cysteine protease in osteoclasts, it was postulated that molecules that inhibit cathepsin K activity could serve as useful therapeutic agents against diseases associated with excessive levels of bone destruction.
It is postulated that PACAP is involved in nociception.
It's postulated that this activity resets the overactive pain-generating areas in brain.
Initially, it was postulated that autophagosomes might play a structural role in replication complex formation.
It is postulated that these findings served as predisposing factors for the patient's catatonic symptoms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com