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In order to investigate the thrombin recognition of the most active and selective compounds, a molecular modeling study has been performed using available Protein Data Bank (PDB) structures as receptor models for docking experiments.
Nevertheless, a few techno-economic and life cycle analyses (LCA) have been performed using available literature to identify potential bottlenecks from environmental as well as techno-economical perspectives and steer the research towards pre-emptive measures.
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The study was performed using available observational data.
Validation was performed using available experimental data on average molecular weights.
The alternatives generation is performed using available information on product design, assembly sequences, and planned production information.
In order to narrow the selection, an initial study was performed using available results from literature to obtain ohmic losses and mode conversion in mitre bends.
To validate our proteomics data, Western blots were performed using available phosphorylation-specific antibodies.
This evaluation was performed using available hospital records.
Our methodology has used standard statistical approaches that can be performed using available software.
Sensitivity analyses will be performed using available cases and per protocol data.
All these steps were performed using available functions in the package geiger (Harmon et al., 2003, script available upon request).
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