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The current study included a subset consisting of 280 postmenopausal patients for whom frozen tumour tissue was still available after hormone receptor assays had been performed in routine practice (Table 1).
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As the quantification of the latter parameters is performed in routine when donating blood, a continuous decrease in their level could be interpreted as a premature sign of a later decrease in hemoglobin mass, which is more complex to assess.
We have presented a registration methodology for accurate alignment between PET and histopathology slices that can be performed in routine pathology settings and that demonstrates an accuracy better than the spatial resolution of the PET scanner.
Image fusion has been impractical and too tedious to be performed in routine work, but in the future, fused images will be used in clinical practice — even in teleradiological consultation.
All of the investigations were performed in routine diabetes outpatient clinics and were in compliance with the Helsinki Declaration (11).
In all patients, at least one diagnostic CT scan of the chest was performed in routine workup.
In case of tumor heterogeneity, areas with the lowest TSR value were considered decisive as is performed in routine pathology to determine tumor differentiation.
MRD testing was performed in routine diagnostic laboratories, with MRD positivity defined as a level of MRD >0.01% (10−4; that is, >1 in 10 000 cells).
In our test, DNA amplification was performed in routine thermal cycler followed by end-point detection using molecular beacon on dark reader or ELISA reader.
Visual evaluation of blood smears is regarded as gold standard for detection of EDTA-PTCP, but only a limited amount of smears will be performed in routine laboratories.
Thirdly, this study was performed in routine conditions, with multiple lecturers who were advised not to modify their sessions with a view to coaching for the test.
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