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Extensive studies of miRNAs have been performed in model plants such as rice and Arabidopsis thaliana.
Extensive studies of miRNAs have been performed in model plants such as rice, Arabidopsis thaliana and other plants.
The latter studies have all been performed in model organisms with a typical lifespan of several years.
Furthermore, most of the analyses on plant APs have been performed in model species such as Arabidopsis[ 7, 11], with little attention paid to woody species like grape.
A large part of these works has been performed in model plant species, inappropriate for human consumption and, correspondingly, not promising for further application as edible vaccines.
However, while the age-related decline in chaperone-mediated autophagy has been documented in mammalian cells, most of the studies on autophagy have been performed in model organisms such as Drosophila, C.elegans and yeast.
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An extensive study of these analogues has not previously been performed in models of breast cancer.
Previous studies on CAR function, however, have been performed in models of advanced cancer types of the colon, prostate and kidney.
Most studies of the pulmonary circulatory effects of hypercapnia have been performed in models with hypoxia-induced pulmonary vasoconstriction (HPV) in either intact animals or isolated lung preparations where vasoconstriction was induced by lowering the inspired oxygenation concentration [ 29– 33].
The beneficial effects of rapamycin on lifespan, cancer and other diseases have largely been performed in models utilizing standard dietary conditions, i.e., normal, low fat rodent chow consisting of largely vegetable matter.
Moreover, these studies were performed in model invertebrates, such as Drosophila melanogaster [20] or C. elegans [21], with few studies carried out on Lepidopteran pests [22]; [22].
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