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Successful combinatorial strategies have already been performed in complex medical situations such as infectious disease [23].
While previous studies have used tissue culture systems to assess GPCR structure-function relationships, detailed molecular analyses of mutated receptors have not been performed in complex and dynamic systems where the cells under study are in contact with neighboring cells and responding to endogenous extracellular signals.
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For evaluation of the fermentation performance in medium containing D-xylose and glucose, the batch fermentations were performed in complex medium in 300 mL shake flasks with a working volume of 200 mL at 35°C.
The first component mode synthesis method is performed in complex space, whereas the second method can be applied in real space.
Although most convertase research has been performed in highly complex protein environments like human plasma, studies performed in semi-purified conditions have significantly improved our understanding of C5 convertases [ 11, 12, 20, 29, 30].
The Fourier transform can be performed in-place on a complex signal, so no additional memory is required.
A considerable amount of numerical studies have been performed in order to understand the complex interactions between soil and pipe (Wijewickreme, 2012).
Experimental tests and numerical finite element (FE) simulations on both the sandwich composite and its separate components have been performed in order to characterise fully the complex mechanical behaviour of such a highly heterogeneous material.
Previous trials evaluating such initiatives have been performed in primary care, or have included complex multidisciplinary interventions.
Genome-wide association studies (GWAS) testing several hundred thousand SNPs have been performed in multiple sclerosis (MS) and other complex diseases.
Hybridization assays with the DNA target were performed in a complex medium by cyclic voltammetry.
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