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HS Trap extraction has been optimized using an optimal design of experiments (O-DOE) approach, considering four instrumental and two sample preparation variables, as well as a blocking factor identified during preliminary assays.
In this work, a continuous API purification process has been optimized using an integrated flowsheet model.
The potential function only contains 210 contacts, one hydrophobic and one torsion parameters, which have been optimized using an interior point algorithm of linear programming.
The method, which has been optimized using an experimental design, involves the use of fibres coated with polydimethylsiloxane (PDMS) and allows the analysis of TCA at very low concentrations (under 500 ng/l) with good accuracy (RSD≤10%).
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The latter is optimized using an iterative LMI solution procedure.
The microextraction technique was optimized using an experimental design, and the analytical performance was evaluated under optimum conditions.
The magnetic flux path was optimized using an equivalent magnetic circuit model to maximize the electromagnetic force.
The extraction parameters for oil extraction from Lycium barbarum seed including extraction pressure, temperature and time were optimized using an orthogonal test design.
The present study evaluated the herbicidal potential of extracts from chicory (Cichorium intybus L). roots on the germination of Echinochloa crusgalli L. Beauv and Amaranthus retroflexus L. Eight ultrasonic assisted-extraction (UAE) conditions were optimized, using an orthogonal matrix design.
The experimental variables that affect the MSPD method, such as the amounts of solid-phase and herbal sample, solvent nature, eluate volume and NaOH concentration were optimized using an experimental design.
The model enables the automated generation of inclusive and flexible ORC cascades and is optimized using a global optimization algorithm.
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