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The new inhibitors, based on a tetra-substituted imidazole scaffold, have been optimized to low nanomolar potency in a biochemical assay following a structure-guided approach.
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The pull-in voltage has been optimized to achieve low phase noise, low power consumption VCO.
The silicon deposition has been optimized to obtain low mechanical stress and allowing thick sacrificial layer deposition.
The framework has been optimized to exhibit low overhead and minimal memory requirements by streaming data with few intermediate input/output operations.
In addition, the modified peninsula-structured diaphragms featuring a center boss have been optimized to achieve ultra-low nonlinearities of 0.018%FFS and 0.07%FFS for the 5 kPa and 3 kPa pressure ranges respectively with higher sensitivities as compared to the CBM (cross beam membrane) and hollow stiffening structures.
The network architecture and parameters were optimized to give low prediction error.
The radial distribution of fissile material was optimized to achieve low bundle internal radial power peaking.
At the receiver, 4CPFSK signal constellation partitioning is optimized to provide low BER for AWGN and fading channels as in [9].
The In0.53Ga0.47As implant-free quantum-well device architecture is optimized to achieve low leakage and high transistor performance by using ensemble Monte Carlo and TCAD simulations tools.
Although previous fMRI studies have used event-related designs to isolate phase specific activity, this study differed in that design and analysis methods were optimized to ensure low multicollinearity between the conditions of interest: the duration of the intermediate phase (maintenance) was varied and load was selectively modeled for the encoding and retrieval phases.
The two-round amplification kit is optimized to amplify low volumes and poor quality RNA for Affymetrix array analysis.
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