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Finally, sex, sex hormones, aging, diuretic therapy, and experimentally induced hyperuricemia (in rats) have been observed to modulate the intrarenal expression patterns of certain OAT family members [ 17- 20].
S1R has been observed to modulate the activity of several ion channels including IP3 receptors [2,4] and voltage-gated channels selective for potassium [5,6], sodium [7], and calcium [8].
It is reported that the spatial position and arrangement of tryptophanes (W) affect membrane-active peptide adsorption and activity [ 38, 39] and tryptophanes have been observed to modulate hydrophobic mismatches to maintain peptide stability and activity in lipid bilayer membranes [ 40].
These specific interactions, along with general membrane effects, have been observed to modulate GPCR organization.
In addition, the regulation of carotenoid esterification by PYP1 (Pale Yellow Petal 1) has been observed to modulate carotenoid level and chromoplast development in tomato flower, likely via increasing sequestration and limiting degradation.
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Transcutaneous spinal direct current stimulation (tsDCS) of cervical and thoracic spine regions was observed to modulate sensory and motor responses.
The surface charge on the nanoparticles was observed to modulate uptake efficiency, demonstrating a dual function of the surface modifications as tracking labels and as modulators of cell uptake.
Changing the duty cycle of the plasmonic field pulse was observed to modulate the parameters of the stepwise motions: the longer duration of the off phase produced larger displacements of dsDNA between the trapped states.
The low-frequency theta (4 8 Hz) phase was observed to modulate power in the high gamma (80 150 Hz) band, with stronger modulation occurring at higher theta amplitudes.
The present experiment was designed to replicate and extend previous results of an opiate + benzodiazepine interaction in which peripherally administered alprazolam was observed to modulate behavior resulting from intravenous injections of heroin.
Hfq was observed to modulate numerous proteins involved in envelope stress under AMM-2 conditions, including FkpA, SurA, HtrA, NlpB, NmpC, ClpA, SlyD, RseA, RseB, RpoE, OmpF, and HtpG, which were all up-regulated in the Δhfq mutant strain.
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