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Limitations in activity levels have also been observed in younger patients.
However, for patients with chronic kidney disease (CKD), frailty has also been observed in younger age groups [ 1, 2].
Since 2002, however, viral encephalitis has increasingly been observed in younger children, particularly in those <4 years.
However, the significant extension in overall survival (OS) has only been observed in younger patients under 60 years of age by population-based analyses (Table 1) [ 15– 17].
Microstructural white matter abnormalities have also been observed in younger adults with type 1 diabetes (average age 45 years) (36) and in adolescents with type 2 diabetes (37).
Finally, in The Netherlands a constant increase has been observed in younger women indicating that the overall increase is likely to continue.
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Glycosuria has been observed in young nondiabetic HNF1A mutation carriers.
This effect has mainly been observed in young organisms, and as such senescence is considered a natural tumor suppressor mechanism [ 16- 19].
Over the past 30 years, no systemic side-effects on long-term treatment with the topical retinoid have been observed in young adults.
Increased use was observed in younger, less experienced professionals.
Further, a modulation of Nc/CRN amplitudes between compatible and incompatible trials was observed in younger adults, but was absent in older adults.
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