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A severe skewing of myeloid and T cells toward leukemia-supportive and immunosuppressive phenotypes have been observed in patient samples and the Eμ-TCL1 mouse model of CLL.
In fact, similar effects have been observed in patient and phantom data, if 124I and 68Ga are used [27, 28].
Recent studies and clinical trials have found an increased rate of thrombosis with EPO, which has mainly been observed in patient groups with higher than conventional levels of hemoglobin (> 120 g/L).
Also, marked effects of football training on body composition have been observed in patient groups (table 3).
Recently, other fusions have been observed in patient samples that histologically resemble Ewing sarcoma but lack the canonical fusion.
Although the precise functional implication of this finding is unclear, it is not implausible to suggest that this decrease in co-activation may, to some degree, contribute to the cognitive deficits that have been observed in patient MTL3.
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Similar observation has been observed in patients with ADEM [12].
Antimyocardium antibodies (AMA) have been observed in patients with acute myocardial infarction (AMI).
This mutation has also been observed in patients receiving ZDV+ddC and ZDV+ddI.
Various markers of senescence have been observed in patients with neurodegenerative diseases7,8,9; however, a role for senescent cells in the aetiology of these pathologies is unknown.
A lack of correlation between histologic HER2-positivity and tumor uptake of, e.g., zirconium-89 (89Zr -labeled trastuzumab has been observed in patients with breast cancer7,14.
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