Overexpression of the metabolic enzyme BCAT1 has been observed in multiple cancer types.
Pulmonary expression of heme oxygenase has been observed in multiple studies.
Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and dysfunction of both organelles has been observed in multiple diseases1,2,3,4.
Objective tumor responses to TLR9 agonist monotherapy have been observed in multiple tumor types, including both solid tumors and hematologic malignancies.
Perhaps most remarkably, protein aggregation and self-assembly has now been observed in multiple proteins that regulate the DNA damage response.
Forest transitions (FT) occur when socioeconomic development leads to a shift from net deforestation to reforestation; these dynamics have been observed in multiple countries across the globe, including the island of Puerto Rico in the Caribbean.
c-Met was emerging as an attractive target for cancer-targeted therapy because deregulation of c-Met has been observed in multiple tumor types.
Despite requiring a more elaborate network architecture, phase-delayed inhibition has been observed in multiple systems, suggesting that it may provide inherent advantages over simply imposing a high spike threshold.
Let me stress that this isn't the first time coherent quantum effects have been observed in multiple superconducting qubits.
EMT has been observed in multiple biological processes, especially embryonic development.
Also, degradation of SIRT6 by MDM2 has been observed in multiple lines of breast cancer cells (Thirumurthi et al., 2014).
