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There have been multiple changes in front of the camera: Hewer is just the current holder of a chairing baton that passed from the late Whitely to the rather diffident Des Lynam, then subsequently to Des O'Connor and Jeff Stelling.
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Alongside the multiple patterns of ongoing medication use, there often are multiple changes in dose and formulation [ 17].
In the glycolysis pathway, many genes were up-regulated during infection, including genes encoding glucose-6-phosphate isomerase [EC 5.3.1.9], transcripts of which were increased by 14-fold at 12 dai There are multiple changes in expression of genes encoding enzymes of the alpha-linolenic acid pathway leading to several important defense-related compounds, including jasmonic acid.
There may have been multiple changes and pathways in each village, and there may be other mechanisms that have not yet been documented.
Although there were multiple changes found in tcdC in various strains of C. difficile (e.g. 57A, 83, and 1083) that resulted in predicted truncated proteins that are likely not active, these defects do not always correlate with increased toxin expression.
While little overall change in serotypes or STs was evident, multiple changes in the frequency of individual STs and or serotypes may plausibly be ascribed to the introduction of PCV-13.
Mr. Petronio clearly believes in dance: that it can take on Mr. Cave or anyone else, that it can be glamorous and unabashedly theatrical (there are multiple costume changes, in sexy disheveled mode from Tara Subakoff) as well as audacious.
Another is multiple nucleotide changes in a codon.
O-glycosylation of Sp1 with N-acetylglucosamine has been linked to multiple changes in Sp1 function, including altered self-association, altered interaction with basal transcription factors and modulation of its degradation [33], [34], but not its DNA binding activity [35], while phosphorylation has been found to either decrease [36] or increase [37] the DNA binding activity.
It has been shown that multiple changes in structure occur during annealing of SPD-processed nanocrystalline metals and alloys since they contain, in addition to small grains, a high dislocation density and high internal strains [4 7].
The ship's construction was delayed by multiple changes in her design after she was laid down.
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