The cloned viral genomes can be easily modified, which allows researchers to conduct genetic studies and determine viral gene functions.
In response to various stresses (Giudice et al., 2010), Keap1 thiol groups are modified which prevents Nrf2 degradation, and allows Nrf2 to translocate into the nucleus where it can activate transcription of several anti-oxidant genes, including that encoding GCL.
But there was much more: a stolen laptop computer found in Mr. Muhammad's car that contained maps of several shooting scenes; an electronic organizer that contained references to "the Muhammad assinations"; and the Caprice itself, which had been modified to allow a person to stretch out inside the trunk and fire a gun through a hole in the back.
Cacti are desert specialists and in most species the leaves have been dispensed with and the chlorophyll displaced into the trunks, the cellular structure of which has been modified to allow them to store water.
Animals were implanted with chronic electrode assemblies and acclimatized to the recording protocol in their home cage, which had been modified to allow wire attachment.
Disease occurs after the target antigen gliadin has been modified by the enzyme tissue transglutaminase, which allows subsequent presentation in the context of specific HLA molecules [ 19].
Tomato (Solanum lycopersicum cv. 'Moneymaker') was transformed with the choline oxidase gene codA from Arthrobacter globiformis, which was modified to allow for targeting to both chloroplasts and the cytosol.
25-OHD was extracted from 6mm spots and derivatized for analysis by LC-MS/MS using previously described methods [21], [22] which were modified to allow for automation.
These were estimated from calculations of solvent accessible surface using the program EDTSurf, which was modified to allow exclusion of internal cavities [Xu, D., personal communication].
This work builds on earlier work with a cylindrical solenoid of variable pitch based on a design by Leifer, which was modified to allow for the rectangular geometry.
