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MIKC-type genes have functioned in growth and development of plants since their evolution and after multiple duplication events in B. rapa, MIKC-type genes appear to have functionally differentiated in a relatively short time and been maintained as functional genes in the genome to perform more complex functions flower and organ development.
Similar(59)
Such functional modules are maintained as long as mutations leading to new interactions among existing proteins in the pathway are rare.
Taken together, these observations suggest that carA is maintained as a functional protein coding gene, albeit in a truncated form.
The superimposition of these sites onto representative structures of the Hmd enzyme and paralog showed that the enzyme active site is maintained as a functional site in the paralog.
For the majority of gene clusters, however, it is not clear whether the genomic organisation is maintained as a result of functional constraints, or whether it is merely by chance that no chromosomal rearrangements disrupting the complex have become fixed.
COS-7 cells derived from African green monkey kidney and lacking endogenous expression of functional GR were maintained as described previously [ 19].
Human artificial chromosomes (HACs), which carry a fully functional centromere and are maintained as a single-copy episome, are not associated with random mutagenesis and offer greater control over expression of ectopic genes on the HAC.
Age-matched rats were maintained as controls.
Embryos were maintained as standard method.
Cells were maintained as recommended by suppliers.
S2 cells were maintained as described [17].
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