Much progress has been made towards the development of manufacturing infrastructure for plant-made pharmaceuticals (PMP), which typically consist of recombinant proteins applied as vaccine antigens, therapeutic enzymes, or monoclonal antibodies.
After the identification of CXCR4 as a co-receptor for the entry of the HIV virus [6], great efforts have been made towards the development of CXCR4 antagonists.
Significant efforts have been made towards the development of a tissue engineered heart valve (TEHV) for the treatment of congenital valvular disorders.
Matter-wave interferometry and cavity quantum optomechanics are generally considered as potentially winning technological platforms in this context, and considerable efforts have been made towards the development of suitable experimental configurations using levitated spheres or gas-phase molecular or metallic-cluster beams.
Over the last several years, much progress has been made towards the development of safe and effective dengue vaccines and mosquito control strategies can now be supplemented by vaccination.
Several attempts have been made towards the development of better diagnostic tests for TB [ 1].
During the past years, a great effort has been made towards the development of several techniques [ 47] and software applications [ 46] to detect structural variations in genomes.
In recent years, great strides have been made towards the development of safer and more effective biotherapeutics, as well as in the adoption of cost-effective, more efficient, and streamlined manufacturing processes.
During the past decade, significant progresses have been made towards understanding pollen development at each development stage under the molecular level, yet the regulatory mechanisms that control the dynamic pollen development processes remain largely unknown.
Although significant progress has been made towards understanding pollen development at each development stage, yet the dynamic regulatory network remains further characterized, the transcription factors and their target genes involved in the dynamic processes need investigation in deeper.
