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ERMES is ancient but has been lost in several lineages including animals, plants, and SAR (stramenopiles, alveolates and rhizaria).
For instance, if we hypothesized that a secondary palate evolved in the common ancestor of therocephalians and cynodonts, our tree implies that this feature would need to have been lost in several therocephalian subgroups, necessitating four evolutionary changes, as opposed to the three required by our preferred hypothesis.
Writings on more permanent media have also been lost in several ways.
In E. coli, the homologous relEB TAS have been lost in several strains [14].
Planktonic larval stages (zoeae and megalopae) are plesiomorphic for crabs, have rarely been lost in marine crabs, but have been lost in several freshwater/terrestrial lineages [55], [84].
In addition, dynactin4, Arp10, and dynactin2 have been lost in several, two, and 1 branch of the yeasts, respectively.
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Energy is lost in several ways as it flows along these pathways of consumption.
Power and water was lost in several provinces, while overflowing rivers caused flooding, landslides and made roads impassable.
The inner seta is lost in several genera of dirivultids.
The proximal endopodal segment of leg 4 in dirivultids is armed with 1 inner seta at most as in the ancestral state of siphonostomatoids (this seta is lost in several genera of dirivultids).
By visual inspection of the structures, it was found that the WT peptide maintained its middle region (15 24) in the initial α-helical conformation during the whole 20 ns simulations in most of the trajectories at 300 K and at 330 K, but at 360 K the α-helical conformation was lost in several trajectories.
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