Sentence examples for been linked with mutations from inspiring English sources
TPP is regarded as a model for related conditions, known as "channelopathies", which have been linked with mutations in ion channels; the majority of these conditions occurs episodically.
In humans, inheritable breast cancers have been linked with mutations in the breast cancer susceptibility gene, breast cancer 2 early onset (BRCA2), and the lifetime risk of developing breast cancer is high (81 88 %) in females carrying a BRCA2 mutation [ 7, 8].
AD is genetically heterogeneous and has been linked with mutations in genes encoding amyloid precursor protein (APP), presenilin 1 (PS1) and presenilin 2 (PS2) as well as the ε4 allele of apolipoprotein E. Amyloid precursor protein cleavage by the β- and γ-secretase complexes leads to the formation of amyloid-β (Aβ) peptides that can aggregate and form amyloid plaques.
Many inherited diseases are linked with mutations in nuclear lamins and integral proteins of the inner nuclear membrane.
It's known that melanoma risk is linked with mutations at particular genetic hot-spots.
In some, but not in all cases, the lack of binding has been shown to be linked with mutations in a cadherin gene [43] [46].
This finding implies that deafness is linked with mutations in Aspa in Canavan disease.
In both pests, resistance to Cry1Ac is linked with mutations in a gene encoding a cadherin protein that binds Cry1Ac (Morin et al. 2003; Yang et al. 2007).
However, we cannot rule out the possibility that these cases may carry germline variations in other genes which could influence breast cancer susceptibility and which include variants within ESR1 that may be linked with mutation status.
The condition has been linked with genetic mutations in genes that code for certain ion channels that transport electrolytes (sodium and potassium) across cell membranes.
Cancer has been linked with aging since genetic mutations accumulate with age and delayed aging has been associated with lesser incidence of cancers [ 9].
